Add metadata to a Seurat object, handling cell mismatches

Unlike Seurat's AddMetaData, this function handles the case where the metadata data.frame has fewer or more rows than cells in the object. Missing cells get NA values.

Usage

BascetAddMetaData(
  adata,
  metadata,
  columns = NULL,
  subsetCommon = FALSE,
  excludeColumns = c("_index", "cell_index", "taxid_index", "cnt"),
  prefix = NULL
)

Arguments

adata

A Seurat object

metadata

A data.frame with rownames matching cell names

columns

Columns to add. Default: all except excludeColumns

subsetCommon

If TRUE, subset the Seurat object to only cells present in both adata and metadata

excludeColumns

Columns excluded when columns is NULL

prefix

Optional prefix added to column names before appending

Value

The Seurat object with added metadata columns